Nucleotide Databases

Other types of nucleotide sequence databases

• Genomes Server - this gives access to a large number of complete genomes.
  
  
• UniGene - a sequence-cluster database which address the redundancy problem by coalescing sequences that are sufficiently similar that one may reasonably infer that they are derived from the same gene.
  
  
• EMBL-SVA - the 'EMBL Sequence Version Archive' server is a repository of all entries that have been made public since release 1 of the EMBL database. It comprises more than 100 million entries and includes entries pre-dating the first electronic release of the database in 1982.
  

Several specialised sequence databases are also available. Some of these deal with particular classes of sequence:

• RDP - the 'Ribosomal Database Project' provides ribosome related data services to the scientific community, including online data analysis, rRNA derived phylogenetic trees, and aligned and annotated rRNA sequences.
  
  
• HIV-SD - the 'HIV Sequence Database' collects, curates and annotates HIV and SIV sequence data and provides various tools for analysing this data.
  
  
• IMGT - the 'ImMunoGeneTics database' is a database specialising in Immunoglobulins, T cell receptors and the Major Histocompatibility Complex (MHC) of all vertebrate species.

Others nucleotide sequence databases are focussing on particular features such as:

• EPD - the 'Eukaryotic Promoter Database' is an annotated non-redundant collection of eukaryotic POL II promoters, for which the transcription start site has been determined experimentally.
  
  
• REBASE - for restriction enzymes and restriction enzyme sites.
  
  
• GOBASE - is a specialised database of organelle genomes.
  
  
  

• In this next section we will look at genomic databases >>>